Au decorated ZnO thin film: application to DNA sensing

• Main Authors: Foo, K. L., Hashim, U., Voon, C. H., Mohammad, Kashif, Md. Eaqub, Ali
• Format: E-Article
• Language: English
• Published: Springer Berlin Heidelberg 2016
• Subjects: T Technology (General)
• Online Access: http://ir.unimas.my/id/eprint/10321/1/NO%2020%20Au%20decorated%20ZnO%20thin%20film%209abstract%29.pdf; http://ir.unimas.my/id/eprint/10321/; http://link.springer.com/article/10.1007%2Fs00542-015-2572-x

Here we reported the gold nanoparticles (GNPs) decorated ZnO thin films based biosensor for the detection of pork DNA hybridization. Label-free DNA detection is increasingly important in bio diagnostics, food analysis and forensic investigations. The capacitance, permittivity and impedance profiles of the biosensor clearly differentiated the complementary and non-complementary target DNA detection using low-cost dielectric analyzer. In this study, GNPs were used to create an attachment surface between the ZnO thin films and the thiol-modified probe DNA and to enhance the sensitivity of the biosensor up to ~59 %. The ZnO thin films and 35 ± 5 nm in diameters of GNP-coating on their surfaces were confirmed with various types of measurement such as FESEM, XRD, EDX and UV–Vis spectroscopy.