Au decorated ZnO thin film: application to DNA sensing
Here we reported the gold nanoparticles (GNPs) decorated ZnO thin films based biosensor for the detection of pork DNA hybridization. Label-free DNA detection is increasingly important in bio diagnostics, food analysis and forensic investigations. The capacitance, permittivity and impedance prof...
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| Main Authors: | , , , , |
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| Format: | E-Article |
| Language: | English |
| Published: |
Springer Berlin Heidelberg
2016
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| Subjects: | |
| Online Access: | http://ir.unimas.my/id/eprint/10321/1/NO%2020%20Au%20decorated%20ZnO%20thin%20film%209abstract%29.pdf http://ir.unimas.my/id/eprint/10321/ http://link.springer.com/article/10.1007%2Fs00542-015-2572-x |
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| Summary: | Here we reported the gold nanoparticles
(GNPs) decorated ZnO thin films based biosensor for the
detection of pork DNA hybridization. Label-free DNA
detection is increasingly important in bio diagnostics, food
analysis and forensic investigations. The capacitance, permittivity
and impedance profiles of the biosensor clearly
differentiated the complementary and non-complementary
target DNA detection using low-cost dielectric analyzer. In
this study, GNPs were used to create an attachment surface
between the ZnO thin films and the thiol-modified probe
DNA and to enhance the sensitivity of the biosensor up to
~59 %. The ZnO thin films and 35 ± 5 nm in diameters of
GNP-coating on their surfaces were confirmed with various
types of measurement such as FESEM, XRD, EDX and
UV–Vis spectroscopy. |
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