Solubility of Rosmarinic Acid in Supercritical Carbon Dioxide Extraction from Orthosiphon stamineus Leaves

• Main Authors: Ahmad Hazim Abdul Aziz, Nor Faadila Mohd Idrus, Nicky Rahmana Putra, Mohd Azrie Awang, Zuhaili Idham, Hasmadi Mamat, Mohd Azizi Che Yunus
• Format: Article
• Language: English; English
• Published: MDPI 2022
• Subjects: QD1-999 Chemistry; TX341-641 Nutrition. Foods and food supply
• Online Access: https://eprints.ums.edu.my/id/eprint/34244/1/Solubility%20of%20Rosmarinic%20Acid%20in%20Supercritical%20Carbon%20Dioxide%20Extraction%20from%20Orthosiphon%20stamineus%20Leaves%20.pdf; https://eprints.ums.edu.my/id/eprint/34244/2/Solubility%20of%20Rosmarinic%20Acid%20in%20Supercritical%20Carbon%20Dioxide%20Extraction%20from%20Orthosiphon%20stamineus%20Leaves%201.pdf; https://eprints.ums.edu.my/id/eprint/34244/; https://www.mdpi.com/2305-7084/6/4/59; https://doi.org/10.3390/chemengineering6040059

Rosmarinic acid (RA) is present in a broad variety of plants, including those in the Lamiaceae family, and has a wide range of pharmacological effects, particularly antioxidant activity. To extract RA from Orthosiphon stamineus (OS) leaves, a Lamiaceae plant, a suitable extraction process is necessa...