Antioxidant and hypolipidaemic properties of red seaweed, Gracilaria changii
The edible red seaweed, Gracilaria changii, was collected from the coastal area of Sarawak, Malaysia, and evaluated for its hypolipidaemic properties using high cholesterol/high fat (HF) induced male Sprague–Dawley rats. In the in vivo study, the HF diet group showed significantly higher total chole...
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Springer Netherlands
2013
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my.ums.eprints.341312022-09-15T08:06:02Z https://eprints.ums.edu.my/id/eprint/34131/ Antioxidant and hypolipidaemic properties of red seaweed, Gracilaria changii Chan, Pei Teng Patricia @ Patricia Clementina Matanjun Suhaimi Md. Yasir Djuli Acun Darmawan @ Tan Tek Song QK1-989 Botany TX341-641 Nutrition. Foods and food supply The edible red seaweed, Gracilaria changii, was collected from the coastal area of Sarawak, Malaysia, and evaluated for its hypolipidaemic properties using high cholesterol/high fat (HF) induced male Sprague–Dawley rats. In the in vivo study, the HF diet group showed significantly higher total cholesterol (TC), low density lipoprotein cholesterol (LDL-C), atherogenic index (AI) and body weight gain as compared to other treatment groups. At the end of treatment period, rats fed with a HF diet supplemented with 5 % freeze-dried G. changii powder had significantly reduced plasma TC (−39.19 %), LDL-C (−36.36 %), and triglycerides (TG) content (− 25.45 %). Meanwhile, 10 % seaweed powder significantly lowered the plasma TC, LDL-C and TG content by −40.34, −35.95 and −30.91 % respectively, compared to the HF group. The AI of rats supplemented with 10 % seaweed powder was the lowest among the treatment groups and indicates a lowered risk for cardiovascular diseases. The plasma lipid peroxidation of the seaweed powder-fed groups was also significantly lower than the HF group, while the erythrocyte enzyme antioxidant activities of superoxide dismutase, catalase and glutathione peroxidase of the treatment groups were also improved. Diets supplemented with seaweed powder also decreased plasma aspartate aminotransferase and the alanine aminotransferase levels. Springer Netherlands 2013 Article PeerReviewed text en https://eprints.ums.edu.my/id/eprint/34131/1/Antioxidant%20and%20hypolipidaemic%20properties%20of%20red%20seaweed%2C%20Gracilaria%20changii.pdf text en https://eprints.ums.edu.my/id/eprint/34131/3/Antioxidant%20and%20hypolipidaemic%20properties%20of%20red%20seaweed%2C%20Gracilaria%20changii%20_ABSTRACT.pdf Chan, Pei Teng and Patricia @ Patricia Clementina Matanjun and Suhaimi Md. Yasir and Djuli Acun Darmawan @ Tan Tek Song (2013) Antioxidant and hypolipidaemic properties of red seaweed, Gracilaria changii. Journal of Applied Phycology, 26. pp. 987-997. ISSN 0921-8971 (P-ISSN) , 1573-5176 (E-ISSN) https://link.springer.com/content/pdf/10.1007/s10811-013-0135-z.pdf https://doi.org/10.1007/s10811-013-0135-z |
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QK1-989 Botany TX341-641 Nutrition. Foods and food supply Chan, Pei Teng Patricia @ Patricia Clementina Matanjun Suhaimi Md. Yasir Djuli Acun Darmawan @ Tan Tek Song Antioxidant and hypolipidaemic properties of red seaweed, Gracilaria changii |
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The edible red seaweed, Gracilaria changii, was collected from the coastal area of Sarawak, Malaysia, and evaluated for its hypolipidaemic properties using high cholesterol/high fat (HF) induced male Sprague–Dawley rats. In the in vivo study, the HF diet group showed significantly higher total cholesterol (TC), low density lipoprotein cholesterol (LDL-C), atherogenic index (AI) and body weight gain as compared to other treatment groups. At the end of treatment period, rats fed with a HF diet supplemented with 5 % freeze-dried G. changii powder had significantly reduced plasma TC (−39.19 %), LDL-C (−36.36 %), and triglycerides (TG) content (− 25.45 %). Meanwhile, 10 % seaweed powder significantly lowered the plasma TC, LDL-C and TG content by −40.34, −35.95 and −30.91 % respectively, compared to the HF group. The AI of rats supplemented with 10 % seaweed powder was the lowest among the treatment groups and indicates a lowered risk for cardiovascular diseases. The plasma lipid peroxidation of the seaweed powder-fed groups was also significantly lower than the HF group, while the erythrocyte enzyme antioxidant activities of superoxide dismutase, catalase and glutathione peroxidase of the treatment groups were also improved. Diets supplemented with seaweed powder also decreased plasma aspartate aminotransferase and the alanine aminotransferase levels. |
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Article |
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Chan, Pei Teng Patricia @ Patricia Clementina Matanjun Suhaimi Md. Yasir Djuli Acun Darmawan @ Tan Tek Song |
author_facet |
Chan, Pei Teng Patricia @ Patricia Clementina Matanjun Suhaimi Md. Yasir Djuli Acun Darmawan @ Tan Tek Song |
author_sort |
Chan, Pei Teng |
title |
Antioxidant and hypolipidaemic properties of red seaweed, Gracilaria changii |
title_short |
Antioxidant and hypolipidaemic properties of red seaweed, Gracilaria changii |
title_full |
Antioxidant and hypolipidaemic properties of red seaweed, Gracilaria changii |
title_fullStr |
Antioxidant and hypolipidaemic properties of red seaweed, Gracilaria changii |
title_full_unstemmed |
Antioxidant and hypolipidaemic properties of red seaweed, Gracilaria changii |
title_sort |
antioxidant and hypolipidaemic properties of red seaweed, gracilaria changii |
publisher |
Springer Netherlands |
publishDate |
2013 |
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https://eprints.ums.edu.my/id/eprint/34131/1/Antioxidant%20and%20hypolipidaemic%20properties%20of%20red%20seaweed%2C%20Gracilaria%20changii.pdf https://eprints.ums.edu.my/id/eprint/34131/3/Antioxidant%20and%20hypolipidaemic%20properties%20of%20red%20seaweed%2C%20Gracilaria%20changii%20_ABSTRACT.pdf https://eprints.ums.edu.my/id/eprint/34131/ https://link.springer.com/content/pdf/10.1007/s10811-013-0135-z.pdf https://doi.org/10.1007/s10811-013-0135-z |
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