Carpaine promotes proliferation and repair of H9c2 cardiomyocytes after oxidative insults

• Main Authors: Suhaini Sudi, Yee, Zheng Chin, Nur SyafinazWasli, Siat, Yee Fong, Sadia Choudhury Shimmi, Siew, Eng How, Caroline Sunggip
• Format: Article
• Language: English; English
• Published: Multidisciplinary Digital Publishing Institute 2022
• Subjects: RS160-167 Pharmacognosy. Pharmaceutical substances (Plant, animal, and inorganic)
• Online Access: https://eprints.ums.edu.my/id/eprint/33404/1/Carpaine%20promotes%20proliferation%20and%20repair%20of%20H9c2%20cardiomyocytes%20after%20oxidative%20insults.ABSTRCT.pdf; https://eprints.ums.edu.my/id/eprint/33404/2/Carpaine%20promotes%20proliferation%20and%20repair%20of%20H9c2%20cardiomyocytes%20after%20oxidative%20insults.pdf; https://eprints.ums.edu.my/id/eprint/33404/; https://pubmed.ncbi.nlm.nih.gov/35215343/; https://doi.10.3390/ph15020230

Carpaine has long been identified as the major alkaloid in Carica papaya leaves that possess muscle relaxant properties. Limited study on the molecular signaling properties of carpaine urges us to conduct this study that aims to elucidate the mechanism underlying the cardioprotective effect of carpa...