Technical data on the inhibition properties of some medicinal plant extracts towards caseinolytic protease proteolytic subunit of Plasmodium knowlesi

• Main Authors: Raimalynah Abd Razak, Meiny Suzery, Rafida Razali, Zarina Amin, Ruzaidi Azli Mohd Mokhtar, Lee, Ping Chin, Cahyo Budiman
• Format: Article
• Language: English; English
• Published: Elsevier Inc. 2021
• Subjects: RS160-167 Pharmacognosy. Pharmaceutical substances (Plant, animal, and inorganic)
• Online Access: https://eprints.ums.edu.my/id/eprint/32839/1/Technical%20data%20on%20the%20inhibition%20properties%20of%20some%20medicinal%20plant%20extracts%20towards%20caseinolytic%20protease%20proteolytic%20subunit%20of%20Plasmodium%20knowlesi.pdf; https://eprints.ums.edu.my/id/eprint/32839/2/Technical%20data%20on%20the%20inhibition%20properties%20of%20some%20medicinal%20plant%20extracts%20towards%20caseinolytic%20protease%20proteolytic%20subunit%20of%20Plasmodium%20knowlesi2.pdf; https://eprints.ums.edu.my/id/eprint/32839/; https://www.sciencedirect.com/science/article/pii/S2352340921008635; https://doi.org/10.1016/j.dib.2021.107588

Proteolytic subunit of the caseinolytic protease system of Plasmodium knowlesi (Pk-ClpP; EC 3.4.21.92) is considered a viable target for antimalarial drug development to eradicate P. knowlesi malaria infection in Malaysia and Southeast Asian region. Inhibition of this system leads to a disruption in...