The therapeutic potential of curcumin in alleviating N-diethylnitrosamine and iron nitrilotriacetate induced renal cell tumours in mice via inhibition of oxidative stress: Implications for cancer chemoprevention

• Main Authors: Mohammad Iqbal, Muhammad Dawood Shah, Senty, Vun-Sang, Yasumasa Okazaki, Shigeru Okada
• Format: Article
• Language: English; English
• Published: Elsevier Masson 2021
• Subjects: RC31-1245 Internal medicine
• Online Access: https://eprints.ums.edu.my/id/eprint/32372/1/The%20therapeutic%20potential%20of%20curcumin%20in%20alleviating%20N-diethylnitrosamine%20and%20iron%20nitrilotriacetate%20induced%20renal%20cell%20tumours%20in%20mice%20via%20inhibition%20of%20oxidative%20stress%20_ABSTRACT.pdf; https://eprints.ums.edu.my/id/eprint/32372/2/The%20therapeutic%20potential%20of%20curcumin%20in%20alleviating%20N-diethylnitrosamine%20and%20iron%20nitrilotriacetate%20induced%20renal%20cell%20tumours%20in%20mice%20via%20inhibition%20of%20oxidative%20stress.pdf; https://eprints.ums.edu.my/id/eprint/32372/; https://www.sciencedirect.com/science/article/pii/S0753332221004212; https://doi.org/10.1016/j.biopha.2021.111636

This study was designed to reveal the protective effects of dietary supplementation of curcumin against renal cell tumours and oxidative stress induced by renal carcinogen iron nitrilotriacetate (Fe-NTA) in ddY male mice. The results showed that mice treated with a renal carcinogen, Fe-NTA, a 35% re...