Potential chemoprevention of diethylnitrosamine-initiated and 2-acetylaminofluorene-promoted hepatocarcinogenesis by zerumbone from the rhizomes of the subtropical ginger (Zingiber zerumbet)

• Main Authors: Elhassan Taha, Manal Mohamed, Abdul, Ahmad Bustaman, Abdullah, Rasedee, Tengku Ibrahim, Tengku Azmi, Abdel Wahab, Siddig Ibrahim, Mohan, Syam
• Format: Article
• Language: English; English
• Published: Elsevier Ireland Ltd 2010
• Online Access: http://psasir.upm.edu.my/id/eprint/7863/1/Potential%20chemoprevention%20of%20diethylnitrosamine.pdf; http://psasir.upm.edu.my/id/eprint/7863/; http://dx.doi.org/10.1016/j.cbi.2010.04.029

Zerumbone (ZER), a monosesquiterpene found in the subtropical ginger (Zingiber zerumbet Smith), possesses antiproliferative properties to several cancer cells lines, including the cervical, skin and colon cancers. In this study, the antitumourigenic effects of ZER were assessed in rats induced to de...