Changes in body fat measured by DEXA in patients taking different formulations of stavudine

• Main Authors: Yang, Yong, Wilder-Smith, Annelies, Anushia Panchalingam, Naing Oo Tha
• Format: Article
• Language: English
• Published: Taylor and Francis Ltd. 2015
• Subjects: RA1-418.5 Medicine and the state; RA638 Immunity and immunization in relation to public health
• Online Access: https://eprints.ums.edu.my/id/eprint/28984/1/Changes%20in%20body%20fat%20measured%20by%20DEXA%20in%20patients%20taking%20different%20formulations%20of%20stavudine%20ABSTRACT.pdf; https://eprints.ums.edu.my/id/eprint/28984/; https://www.tandfonline.com/doi/abs/10.1310/9FJ9-K45E-A1R8-7WRE; https://doi.org/10.1310/9FJ9-K45E-A1R8-7WRE

Background: Lipoatrophy is a frequent complication of chronic stavudine therapy. Stavudine extended release formulation (stavudine ER) gives lower peak and higher trough levels than the immediate release formulation (stavudine IR), and we hypothesized that the lower peak might result in less lipoatr...