Deep Transcriptome Sequencing of Pediatric Acute Myeloid Leukemia Patients at Diagnosis, Remission and Relapse: Experience in 3 Malaysian Children in a Single Center Study

• Main Authors: Siti Hawa Osman, Nadiah Abu, Habsah Aziz, Yock Ping Chow1, Wan Fahmi Wan Mohamad Nazarie, Nurul-Syakima Ab Mutalib, Hamidah Alias, Rahman Jamal
• Format: Article
• Language: English; English
• Published: 2020
• Subjects: Q Science (General)
• Online Access: https://eprints.ums.edu.my/id/eprint/26080/1/Deep%20Transcriptome%20Sequencing%20of%20Pediatric%20Acute%20Myeloid%20Leukemia%20Patients%20at%20Diagnosis%2C%20Remission%20and%20Relapse.pdf; https://eprints.ums.edu.my/id/eprint/26080/2/Deep%20Transcriptome%20Sequencing%20of%20Pediatric%20Acute%20Myeloid%20Leukemia%20Patients%20at%20Diagnosis%2C%20Remission%20and%20Relapse1.pdf; https://eprints.ums.edu.my/id/eprint/26080/; https://doi.org/10.3389/fgene.2020.00066

Among the many types of leukemia, acute myeloid leukemia (AML) affects 20% of diagnosed hematological malignancies in pediatric patients (Meshinchi and Arceci, 2007; de Rooij et al., 2015). Standard chemotherapy regimen remains as the first line treatment for pediatric AML, however nearly 40% of AML...