Effective response metric (ERM-D8) using time-series gene expression profiling at diagnosis and day 8 of remission-induction therapy is a novel early prognostic marker to predict relapse in childhood acute lymphoblastic leukemia (ALL) - a Malaysia-Singapore all study

• Main Authors: Yeoh, A.E.J., Li, Z., Dong, D., Lu, Y., Trka, J., Kham, S.K.Y., Tan, A.M., Ariffin, H., Wong, L.S.
• Format: Article
• Published: American Society of Hematology 2014
• Subjects: R Medicine
• Online Access: http://eprints.um.edu.my/15409/

BACKGROUND ALL is the most common form of childhood cancer with >80% cured with contemporary treatment protocols. Accurate risk stratification in childhood ALL is essential to avoid under- and over-treatment. Currently, we use presenting clinical, biological features, and minimal residual dise...