Lack of correlation between X-ray repair cross-complementing group 1 gene polymorphisms and the susceptibility to coloretal cancer in a Malaysian cohort

• Main Authors: Lau, Tze pheng, Lian, Lay hoong, Cheah, Phaik Leng, Looi, Lai Meng, Roslani April C., Goh, Khean-Lee, Lee, Ping Chin, Chua, Kek Heng
• Format: Article
• Language: English
• Published: 2017
• Subjects: RC Internal medicine
• Online Access: https://eprints.ums.edu.my/id/eprint/20445/1/Lack%20of%20correlation%20between%20X.pdf; https://eprints.ums.edu.my/id/eprint/20445/; https://doi.org/10.1097/CEJ.0000000000000336

X-ray repair cross-complementing group 1 (XRCC1) is one of the key components in the base excision repair pathway that repairs erroneous DNA lesions and removes nonbulky base adducts for the maintenance of genome integrity. Studies have revealed that differences in individual DNA repair capacity can...