A hybrid of ant colony optimization, genetic algorithm and flux balance analysis for optimization of succinic acid production in Escherichia coli

• Main Authors: Tan, Jun Bin, Choon, Yee Wen, Moorthy, Kohbalan, Hasyiya Karimah, Adli, Muhammad Akmal, Remli, Mohd Arfian, Ismail, Zuwairie, Ibrahim, Mohd Saberi, Mohamad
• Format: Article
• Language: English
• Published: World Scientific Publishing 2023
• Subjects: QA75 Electronic computers. Computer science; QH426 Genetics
• Online Access: http://umpir.ump.edu.my/id/eprint/43509/1/A%20hybrid%20of%20ant%20colony%20optimization%2C%20genetic%20algorithm%20and%20flux%20balance%20analysis%20for%20optimization%20of%20succinic%20acid%20production%20in%20Escherichia%20coli.pdf; http://umpir.ump.edu.my/id/eprint/43509/; https://doi.org/10.1142/S179396232350040X; https://doi.org/10.1142/S179396232350040X

Succinic acid, also known as dicarboxylic acid, is one of the biochemical products chemically produced from Escherichia coli (E. coli) metabolism. However, by using conventional methods succinic acid cannot be produced sufficiently and it is costly. Hence, there is a lot of ongoing research on E. co...