Dissolution and biological assessment of cancer-targeting nano-ZIF-8 in zebrafish embryos

• Main Authors: Nurul Akmarina, Mohd Abdul Kamal, Emilia, Abdulmalek, Sharida, Fakurazi, Cordova, Kyle E.
• Format: Article
• Language: English; English
• Published: ACS Publications 2022
• Subjects: RC Internal medicine; TP Chemical technology
• Online Access: http://umpir.ump.edu.my/id/eprint/43166/1/Dissolution%20and%20Biological%20Assessment%20of%20Cancer-Targeting.pdf; http://umpir.ump.edu.my/id/eprint/43166/2/Dissolution%20and%20biological%20assessment%20of%20cancer-targeting_ABST.pdf; http://umpir.ump.edu.my/id/eprint/43166/; https://doi.org/10.1021/acsbiomaterials.2c00186; https://doi.org/10.1021/acsbiomaterials.2c00186

Cancer-targeting nanotherapeutics offer promising opportunities for selective delivery of cytotoxic chemotherapeutics to cancer cells. However, the understanding of dissolution behavior and safety profiles of such nanotherapeutics is scarce. In this study, we report the dissolution profile of a canc...