ZIF-90 nanoparticles modified with a homing peptide for targeted delivery of cisplatin

• Main Authors: Abubakar, Adamu, Abdulmalek, Emilia, Wan Ibrahim, Wan Norhamidah, Cordova, Kyle E., Abdul Rahman, Mohd Basyaruddin
• Format: Article
• Published: Frontiers Research Foundation 2022
• Online Access: http://psasir.upm.edu.my/id/eprint/102659/; https://www.frontiersin.org/articles/10.3389/fchem.2022.1076350/full

To improve the selective delivery of cisplatin (Cis) to cancer cells, we report and establish the significance of active, targeting drug delivery nanosystems for efficient treatment of lung cancer. Specifically, pH-responsive nano-sized zeolitic imidazolate framework (nZIF-90) was synthesized, post-...