Simulation of lovastatin production in solid-state fermentation via oil palm frond

• Main Authors: Nata, N. A., Farhan, Mohd Said, Shalyda, Md Shaarani, Noorlisa, Harun
• Format: Article
• Language: English
• Published: Universiti Malaysia Pahang 2021
• Subjects: TP Chemical technology
• Online Access: http://umpir.ump.edu.my/id/eprint/33067/1/Simulation%20of%20lovastatin%20production%20in%20solid%20state%20fermentation.pdf; http://umpir.ump.edu.my/id/eprint/33067/; https://doi.org/10.15282/jceib.v7i2.6755; https://doi.org/10.15282/jceib.v7i2.6755

Lovastatin is a potent drug for lowering the blood cholesterol. It is a competitive inhibitor of 3-hyroxy3-methyl glutaryl coenzyme A (HMG-CoA) reductase, which is a key enzyme in the cholesterol production pathway. Lovastatin increases the good cholesterol or high-density lipoproteins to prevent th...