Lyophilized amorphous dispersion of telmisartan in a combined carrier–alkalizer system: formulation development and in vivo study

Telmisartan suffers from low oral bioavailability due to its poor water solubility. The research work presents a formulation of solid dispersed (SD) telmisartan formulation as a ternary mixture of a drug, a polymeric carrier (poly(vinylpyrrolidone) (PVP) K30), and an alkalizer (Na2CO3). The preparat...

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Bibliographic Details
Main Authors: Al-Japairai, Khater A. S., Alkhalidi, Hala M., Mahmood, Syed, Almurisi, Samah H., Doolaanea, Abd Almonem, Al-Sindi, Taha A., Chatterjee, Bappaditya
Format: Article
Language:English
Published: American Chemical Society 2020
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Online Access:http://umpir.ump.edu.my/id/eprint/30970/1/Lyophilized%20amorphous%20dispersion%20of%20telmisartan%20in%20a%20combined%20carrier.pdf
http://umpir.ump.edu.my/id/eprint/30970/
https://doi.org/10.1021/acsomega.0c04588
https://doi.org/10.1021/acsomega.0c04588
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