Reaction equilibrium of the ω-transamination of (S)-Phenylethylamine: experiments and ePC-SAFT modeling

• Main Authors: Voges, Matthias, Rohana, Abu, Gundersen, Maria T., Held, Christoph, Woodley, John M., Sadowski, Gabriele
• Format: Article
• Language: English
• Published: American Chemical Society 2017
• Subjects: TP Chemical technology
• Online Access: http://umpir.ump.edu.my/id/eprint/29124/1/Reaction%20equilibrium%20of%20the%20%CF%89-transamination%20of%20%28S%29-Phenylethylamine.pdf; http://umpir.ump.edu.my/id/eprint/29124/; https://doi.org/10.1021/acs.oprd.7b00078; https://doi.org/10.1021/acs.oprd.7b00078

This work focuses on the thermodynamic equilibrium of the ω-transaminase-catalyzed reaction of (S)-phenylethylamine with cyclohexanone to acetophenone and cyclohexylamine in aqueous solution. For this purpose, the equilibrium concentrations of the reaction were experimentally investigated under vary...