Self-assembled insulin and nanogels polyelectrolyte complex (Ins/NGs-PEC) for oral insulin delivery: Characterization, lyophilization and in-vivo evaluation
Introduction: Insulin is given by injection, because when administered orally, it would be destroyed by enzymes in the digestive system, hence only about 0.1% reaches blood circulation. The purpose of the present study was to use pH sensitive polyelectrolyte methyl methacrylate (MMA)/itaconic acid (...
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| Main Authors: | , , , |
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| Format: | Article |
| Language: | English |
| Published: |
Dovepress
2019
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| Subjects: | |
| Online Access: | http://umpir.ump.edu.my/id/eprint/27329/1/Self-assembled%20insulin%20and%20nanogels%20polyelectrolyte%20complex.pdf http://umpir.ump.edu.my/id/eprint/27329/ https://doi.org/10.2147/IJN.S199507 https://doi.org/10.2147/IJN.S199507 |
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