Design, synthesis and cytotoxic effects of curcumin derivatives on K562, MCF-7 and MDA-MB-231 cancer cell lines

• Main Authors: Akhtar, Muhammad Nadeem, Siti Noor Hajar, Zamrus, Yeap, Swee Keong, Noorjahan Banu, Alitheen, Seema, Zareen
• Format: Conference or Workshop Item
• Language: English
• Published: 2018
• Subjects: T Technology (General)
• Online Access: http://umpir.ump.edu.my/id/eprint/21333/1/57.1%20Design%2C%20synthesis%20and%20cytotoxic%20effects%20of%20curcumin%20derivatives%20on%20K562%2C%20MCF-7%20and%20MDA-MB-231%20cancer%20cell%20lines.pdf; http://umpir.ump.edu.my/id/eprint/21333/

Curcumin is one of the leading compound extracted from the dry powder of Curcuma longa (Zingiberaceae family), which possess several pharmacological properties. However, in vivo administration exhibited limited applications in cancer therapies. Twenty four curcumin derivatives were synthesized, comp...