Design, synthesis and cytotoxic effects of curcuminoids on HeLa, K562, MCF-7 and MDA-MB-231 cancer cell lines

• Main Authors: Zamrus, Siti Noor Hajar, Akhtar, Muhammad Nadeem, Yeap, Swee Keong, Quah, Ching Kheng, Loh, Wan-Sin, Mohammed Alitheen, Noorjahan Banu, Zareen, Seema, Tajuddin, Saiful Nizam, Hussin, Yazmin, Ali Shah, Syed Adnan
• Format: Article
• Language: English
• Published: SpringerOpen 2018
• Online Access: http://psasir.upm.edu.my/id/eprint/72196/1/Design%2C%20synthesis%20and%20cytotoxic%20effects%20of%20curcuminoids%20.pdf; http://psasir.upm.edu.my/id/eprint/72196/; https://bmcchem.biomedcentral.com/articles/10.1186/s13065-018-0398-1

Background Curcumin is one of the leading compound extracted from the dry powder of Curcuma longa (Zingiberaceae family), which possess several pharmacological properties. However, in vivo administration exhibited limited applications in cancer therapies. Results Twenty-four curcumin derivative...