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DNA cleavage activiti in two Malaysian tropical fruit for future nutraceutical development

The constantly increasing demand for nutraceuticals is paralleled by a more pronounced request for natural resources and health-promoting foods. Therefore, the present study was conducted to determine DNA cleavage activity from natural resources extract that can help in nutraceutical development. A....

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Main Author: Nur Hazerra Mohd Zakaria
Format: Undergraduate Final Project Report
Published: 2013
Online Access:http://discol.umk.edu.my/id/eprint/5845/
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spelling my.umk.eprints.58452022-05-23T08:43:27Z http://discol.umk.edu.my/id/eprint/5845/ DNA cleavage activiti in two Malaysian tropical fruit for future nutraceutical development Nur Hazerra Mohd Zakaria The constantly increasing demand for nutraceuticals is paralleled by a more pronounced request for natural resources and health-promoting foods. Therefore, the present study was conducted to determine DNA cleavage activity from natural resources extract that can help in nutraceutical development. A. carambola and C. maxima extract are well known tropical fruits of Malaysia. They are rich source of phytochemical as well as exhibited various pharmacological activities. The DNA cleavage activity was carried out against E.coli plasmid DNA by gel electrophoresis. Different concentrations of fruit extracts ranging from 5121 — 25111 were checked for the activity. The results showed that both ethanolic and aqueous extracts of C. maxima were better DNA cleaving agent as compared to A. carambola. This suggests C. maxima have greater potential for therapeutic applications due to its ability of maximum bacterial DNA cleavage up to the linear form. Therefore, further research is warranted in order to determine nutraceutical potential of both fruits. 2013 Undergraduate Final Project Report NonPeerReviewed Nur Hazerra Mohd Zakaria (2013) DNA cleavage activiti in two Malaysian tropical fruit for future nutraceutical development. Undergraduate Final Project Report thesis, Faculty of Agro - Based Industry. (Submitted)
institution Universiti Malaysia Kelantan
building Perpustakaan Universiti Malaysia Kelantan
collection Institutional Repository
continent Asia
country Malaysia
content_provider Universiti Malaysia Kelantan
content_source UMK Institutional Repository
url_provider http://umkeprints.umk.edu.my/
description The constantly increasing demand for nutraceuticals is paralleled by a more pronounced request for natural resources and health-promoting foods. Therefore, the present study was conducted to determine DNA cleavage activity from natural resources extract that can help in nutraceutical development. A. carambola and C. maxima extract are well known tropical fruits of Malaysia. They are rich source of phytochemical as well as exhibited various pharmacological activities. The DNA cleavage activity was carried out against E.coli plasmid DNA by gel electrophoresis. Different concentrations of fruit extracts ranging from 5121 — 25111 were checked for the activity. The results showed that both ethanolic and aqueous extracts of C. maxima were better DNA cleaving agent as compared to A. carambola. This suggests C. maxima have greater potential for therapeutic applications due to its ability of maximum bacterial DNA cleavage up to the linear form. Therefore, further research is warranted in order to determine nutraceutical potential of both fruits.
format Undergraduate Final Project Report
author Nur Hazerra Mohd Zakaria
spellingShingle Nur Hazerra Mohd Zakaria
DNA cleavage activiti in two Malaysian tropical fruit for future nutraceutical development
author_facet Nur Hazerra Mohd Zakaria
author_sort Nur Hazerra Mohd Zakaria
title DNA cleavage activiti in two Malaysian tropical fruit for future nutraceutical development
title_short DNA cleavage activiti in two Malaysian tropical fruit for future nutraceutical development
title_full DNA cleavage activiti in two Malaysian tropical fruit for future nutraceutical development
title_fullStr DNA cleavage activiti in two Malaysian tropical fruit for future nutraceutical development
title_full_unstemmed DNA cleavage activiti in two Malaysian tropical fruit for future nutraceutical development
title_sort dna cleavage activiti in two malaysian tropical fruit for future nutraceutical development
publishDate 2013
url http://discol.umk.edu.my/id/eprint/5845/
_version_ 1763303611479097344
score 13.18916

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