Effect of antisense oligodeoxynucleotides for ICAM-1 on renal ischaemia-reperfusion injury in the anaesthetised rat

• Main Authors: Kiew, Lik Voon, Munavvar, A.S., Law, C.H., Azizan, A.N., Nazarina, A.R., Sidik, K., Johns, E.J.
• Format: Article
• Language: English
• Published: Wiley 2004
• Subjects: R Medicine
• Online Access: http://eprints.um.edu.my/8527/1/Effect_of_antisense_oligodeoxynucleotides_for_ICAM-1_on_renal_ischaemia-reperfusion_injury_in_the_anaesthetised_rat.pdf; http://eprints.um.edu.my/8527/; http://onlinelibrary.wiley.com/doi/10.1113/jphysiol.2004.061788/abstract

An antisense oligodeoxynucleotide (As-ODN) to the 3' untranslated region of the mRNA sequence expressing the intracellular adhesion molecule-1 (ICAM-1) was employed to determine ICAM-1's role in renal ischaemia-reperfusion injury in the rat. Wistar-Kyoto rats receiving i.v. either lipofect...