Efficient rate enhancement due yo intramolecular general base (IGB) assistance in the hydrolysis of N-(O-Hydroxyphenyl)Phthalimide

The rates of the hydrolyses of N-(o-hydroxyphenyl)phthalimide (1) and N-(o-methoxyphenyl)phthalimide (2), studied at different pH, show that the hydrolysis of 1 involves intramolecular general base (IGB) assistance where the o-O- group of ionized 1 acts as IGB and H2O as the reactant. The rate enhan...

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Bibliographic Details
Main Authors: Ariffin, Azhar, Khan, M.N., Sim, Y.L.
Format: Article
Published: 2007
Subjects:
Online Access:http://eprints.um.edu.my/8053/
http://www.scopus.com/inward/record.url?eid=2-s2.0-34047230718&partnerID=40&md5=577b2d282c7049a69536f1ff248140c3
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