Effects Of Mixed Aqueous-Organic Cosolvents On The Rates Of Cleavage Of N-(2'-Hydroxyphenyl)Phthalimide (1) And N-(2'-Methoxyphenyl)-Phthalimide (2) In Alkaline Media

• Main Authors: Ariffin, Azhar, Khan, M.N., Abdullah, N., Sim, Y.L.
• Format: Article
• Published: 2007
• Subjects: QD Chemistry
• Online Access: http://eprints.um.edu.my/8048/; http://www.ingentaconnect.com/content/stl/prk/2007/00000032/00000002/art00001?token=005013f9aa141333c4a2f7a3f6a763b4767473e55466f4f6d62222c227e3725303329768deef3ed0

The effects of mixed H2O-OCS (where organic cosolvents (OCS) = methanol, ethanol, 1-propanol, 2-propanol, 1,4-dioxan and acetonitrile) on the first-order rate constants, k(obs), for hydrolysis of I at 1.0 X 10(-3) M NaOH and 2 at 2.0 x 10(-3) M NaOH show a nonlinear decrease in k(obs), with increasi...