Genetic polymorphism of cytochrome P450 2C19 in healthy Malaysian subjects

• Main Authors: Yang, Y.S., Wong, L.P., Lee, T.C., Mustafa, A.M., Mohamed, Zahurin, Lang, C.C.
• Format: Article
• Published: Blackwell Publishing 2004
• Subjects: R Medicine
• Online Access: http://eprints.um.edu.my/7623/; https://doi.org/10.1111/j.1365-2125.2004.02144.x

Aims Impaired S-mephenytoin 4'-hydroxylation is a well-described genetic polymorphism affecting drug metabolism in humans. Although ethnic differences in its distribution of polymorphism has been described, it is not known whether there is an ethnic heterogeneity of the structure and expression...