Factors affecting nucleolytic efficiency of some ternary metal complexes with DNA binding and recognition domains. Crystal and molecular structure of Zn(phen)(edda)
The binding selectivity of the M(phen)(edda) (M = Cu, Co, Ni, Zn; phen = 1,10-phenanthroline, edda = ethylenediaminediacetic acid) complexes towards ds(CG)(6), ds(AT)(6) and ds(CGCGAATTCGCG) B-form oligonucleotide duplexes were studied by CD spectroscopy and molecular modeling. The binding mode is i...
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Main Authors: | , , , , , , , , |
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Format: | Article |
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2008
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Online Access: | http://eprints.um.edu.my/6950/ http://ac.els-cdn.com/S0162013408001803/1-s2.0-S0162013408001803-main.pdf?_tid=8d8bc3fa-86e0-11e2-a8e6-00000aab0f02&acdnat=1362631158_ce15151c933662a1b64fe1044bcbd070 |
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