Alpha-tocopherol nanodispersions: preparation, characterization and stability evaluation
A top down approach based on emulsification-evaporation technique was used to prepare nanodispersion of α-tocopherol. Physicochemical properties of the prepared nanodispersions were investigated under combination of the processing parameters (pressure and cycle) and ratio of aqueous:organic. Storag...
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my.um.eprints.68782013-07-09T01:21:09Z http://eprints.um.edu.my/6878/ Alpha-tocopherol nanodispersions: preparation, characterization and stability evaluation Cheong, J.N. Tan, C.P. Man, Y.B.C. Misran, M. QD Chemistry A top down approach based on emulsification-evaporation technique was used to prepare nanodispersion of α-tocopherol. Physicochemical properties of the prepared nanodispersions were investigated under combination of the processing parameters (pressure and cycle) and ratio of aqueous:organic. Storage study was performed for 3 months to evaluate the stability of all the prepared nanodispersions. The results showed that homogenization pressure have significant (P < 0.05) influence on the droplet diameter and size distribution. On the contrary, the processing cycle had not significant (P > 0.05) effect on the droplet diameter and size distribution of the prepared nanodispersion. Droplet diameters in the range of 90-120 nm were obtained for the prepared α-tocopherol nanodispersions. During storage duration, there were no significant (P > 0.05) changes in mean diameters while the concentrations of α-tocopherol were significantly (P < 0.05) reduced for all prepared nanodispersions. In general, it is shown that emulsification-evaporation technique can be used as a suitable technique for the production of α-tocopherol nanodispersions with narrow size distribution. 2008 Article PeerReviewed Cheong, J.N. and Tan, C.P. and Man, Y.B.C. and Misran, M. (2008) Alpha-tocopherol nanodispersions: preparation, characterization and stability evaluation. Journal of Food Engineering, 89 (2). pp. 204-209. ISSN 02608774 10.1016/j.jfoodeng.2008.04.018 |
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QD Chemistry Cheong, J.N. Tan, C.P. Man, Y.B.C. Misran, M. Alpha-tocopherol nanodispersions: preparation, characterization and stability evaluation |
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A top down approach based on emulsification-evaporation technique was used to prepare nanodispersion of α-tocopherol. Physicochemical properties of the prepared nanodispersions were investigated under combination of the processing parameters (pressure and cycle) and ratio of aqueous:organic. Storage study was performed for 3 months to evaluate the stability of all the prepared nanodispersions. The results showed that homogenization pressure have significant (P < 0.05) influence on the droplet diameter and size distribution. On the contrary, the processing cycle had not significant (P > 0.05) effect on the droplet diameter and size distribution of the prepared nanodispersion. Droplet diameters in the range of 90-120 nm were obtained for the prepared α-tocopherol nanodispersions. During storage duration, there were no significant (P > 0.05) changes in mean diameters while the concentrations of α-tocopherol were significantly (P < 0.05) reduced for all prepared nanodispersions. In general, it is shown that emulsification-evaporation technique can be used as a suitable technique for the production of α-tocopherol nanodispersions with narrow size distribution. |
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Article |
author |
Cheong, J.N. Tan, C.P. Man, Y.B.C. Misran, M. |
author_facet |
Cheong, J.N. Tan, C.P. Man, Y.B.C. Misran, M. |
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Cheong, J.N. |
title |
Alpha-tocopherol nanodispersions: preparation, characterization and stability evaluation |
title_short |
Alpha-tocopherol nanodispersions: preparation, characterization and stability evaluation |
title_full |
Alpha-tocopherol nanodispersions: preparation, characterization and stability evaluation |
title_fullStr |
Alpha-tocopherol nanodispersions: preparation, characterization and stability evaluation |
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Alpha-tocopherol nanodispersions: preparation, characterization and stability evaluation |
title_sort |
alpha-tocopherol nanodispersions: preparation, characterization and stability evaluation |
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2008 |
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http://eprints.um.edu.my/6878/ |
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1643687906107195392 |
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13.160551 |