A bioequivalence comparison of two formulations of rifampicin (300- vs 150-mg capsules): An open-label, randomized, two-treatment, two-way crossover study in healthy volunteers

• Main Authors: Chik, Zamri, Basu, Roma Choudhury, Pendek, Rokiah, Lee, Toong Chow, Mohamed, Zahurin
• Format: Article
• Language: English
• Published: Elsevier 2010
• Subjects: R Medicine
• Online Access: http://eprints.um.edu.my/5094/1/Chik-2010-A_Bioequivalence_Com.pdf; http://eprints.um.edu.my/5094/; https://doi.org/10.1016/j.clinthera.2010.09.006

Background: Rifampicin is a semisynthetic antibiotic derivative of rifamycin used worldwide for the treatment of various forms of tuberculosis. Objective: The objective of this study was to compare, under fasting conditions in healthy volunteers, the rate and extent of absorption of a generic rifamp...