Mimotopes of the Vi antigen of Salmonella enterica serovar typhi identified from phage display peptide library

• Main Authors: Tang, Swee-Seong, Tan, Wen-Siang, Devi, Shamala, Wang, Lin Fa, Pang, Tikki, Thong, Kwai Lin
• Format: Article
• Published: American Society for Microbiology 2003
• Subjects: Q Science (General); QH Natural history; R Medicine (General)
• Online Access: http://eprints.um.edu.my/478/; https://doi.org/10.1128/CDLI.10.6.1078-1084.2003

The capsular polysaccharide Vi antigen (ViCPS) is an essential virulence factor and also a protective antigen of Salmonella enterica serovar Typhi. A random 12-mer phage-displayed peptide library was used to identify mimotopes (epitope analogues) of this antigen by panning against a ViCPS-specific m...