TLR2-induced cytokine responses may characterize HIV-infected patients experiencing mycobacterial immune restoration disease

• Main Authors: Tan, Dino B.A., Lim, Andrew, Yean, K. Yong, Ponnampalavanar, Sasheela, Omar, Sharifah Faridah Syed, Kamarulzaman, Adeeba, French, Martyn A., Price, Patricia
• Format: Article
• Published: Lippincott Williams & Wilkins 2011
• Subjects: R Medicine
• Online Access: http://eprints.um.edu.my/4620/; https://doi.org/10.1097/QAD.0b013e328348fb18

Objectives: Most HIV patients who experience Mycobacterium tuberculosis-associated immune restoration disease (TB IRD) display elevated interferon-gamma (IFN gamma) responses against mycobacterial antigens, but these can occur without an IRD. Recognition of mycobacteria-associated molecular patterns...