Differential Response of Gestational Tissues to TLR3 Viral Priming Prior to Exposure to Bacterial TLR2 and TLR2/6 Agonists

• Main Authors: Rasheed, Zahirrah B. M., Lee, Yun S., Kim, Sung H., Rai, Ranjit K., Ruano, Camino S. M., Anucha, Eberechi, Sullivan, Mark H. F., MacIntyre, David A., Bennett, Phillip R., Sykes, Lynne
• Format: Article
• Published: Frontiers Media SA 2020
• Subjects: R Medicine
• Online Access: http://eprints.um.edu.my/36476/

Background:Infection/inflammation is an important causal factor in spontaneous preterm birth (sPTB). Most mechanistic studies have concentrated on the role of bacteria, with limited focus on the role of viruses in sPTB. Murine studies support a potential multi-pathogen aetiology in which a double or...