Clustering of HR + /HER2-breast cancer in an Asian cohort is driven by immune phenotypes

• Main Authors: Pan, Jia-Wern, Ragu, Mohana, Chan, Wei-Qin, Hasan, Siti Norhidayu, Islam, Tania, Teoh, Li-Ying, Jamaris, Suniza, See, Mee-Hoong, Yip, Cheng-Har, Rajadurai, Pathmanathan, Looi, Lai Meng, Taib, Nur Aishah Mohd, Rueda, Oscar M., Caldas, Carlos, Chin, Suet-Feung, Lim, Joanna, Teo, Soo Hwang
• Format: Article
• Published: BMC 2024
• Subjects: R Medicine
• Online Access: http://eprints.um.edu.my/45297/; https://doi.org/10.1186/s13058-024-01826-5

Breast cancer exhibits significant heterogeneity, manifesting in various subtypes that are critical in guiding treatment decisions. This study aimed to investigate the existence of distinct subtypes of breast cancer within the Asian population, by analysing the transcriptomic profiles of 934 breast...