Functionalization of poly (lactic-co-glycolic acid) nano-calcium sulphate and fucoidan 3D scaffold using human bone marrow mesenchymal stromal cells for bone tissue engineering application

• Main Authors: Shaz, Norshazliza, Maran, Sathiya, Genasan, Krishnamurithy, Choudhary, Rajan, Alias, Rodianah, Swamiappan, Sasikumar, Kamarul, Tunku, Raghavendran, Hanumanth Rao Balaji
• Format: Article
• Published: Elsevier 2024
• Subjects: RB Pathology
• Online Access: http://eprints.um.edu.my/44277/; https://doi.org/10.1016/j.ijbiomac.2023.128059

This study aimed to functionalize a novel porous PLGA (Poly lactic-co-glycolic acid) composite scaffold in combination with nano-calcium sulphate (nCS) and/or fucoidan (FU) to induce osteogenic differentiation of human bone marrow stromal cells. The composite scaffolds (PLGA-nCS-FU, PLGA-nCS or PLGA...