Human bone marrow-derived Mesenchymal stem cells suppress T cell proliferation by inducing cell cycle arrest

• Main Authors: Tong, Chih Kong, Sarmadi, Vahid Hosseinpour, Vidyadaran, Sharmili, Saiful Yazan, Latifah, Seow, Heng Fong, Ramasamy, Rajesh
• Format: Article
• Language: English
• Published: Faculty of Medicine and Health Sciences, University Putra Malaysia 2008
• Online Access: http://psasir.upm.edu.my/id/eprint/15045/1/Human%20bone%20marrow-derived%20Mesenchymal%20stem%20cells%20suppress%20T%20cell%20proliferation%20by%20inducing%20cell%20cycle%20arrest.pdf; http://psasir.upm.edu.my/id/eprint/15045/; http://www.medic.upm.edu.my/dokumen/FKUSK1_MJMHS_2008V04N1_OP02.pdf

Objective: Mesenchymal stem cells (MSC) are common residents of bone marrow and are defined by their higher self-renewal ability and multilineage differentiation. MSC play an important role in supporting haematopoiesis and therefore are implicated in influencing immune responses. In line with this,...