Combination treatment of TRPV4 agonist with cisplatin promotes vessel normalization in an animal model of oral squamous cell carcinoma

• Main Authors: Yahya, Farhana, Bakri, Marina Mohd, Hossain, Mohammad Zakir, Rahman, Syarifah Nur Syed Abdul, Alabsi, Aied Mohammed, Ramanathan, Anand
• Format: Article
• Published: MDPI 2022
• Subjects: R Medicine; RK Dentistry
• Online Access: http://eprints.um.edu.my/41329/

Oral squamous cell carcinoma (OSCC) is the sixth most common malignancy in the world. Transient receptor potential vanilloid 4 (TRPV4) channel has been shown to be involved in angiogenesis in multiple types of tumors. However, not much is known about TRPV4 ` s involvement in OSCC. Thus, in this stud...