Aberrant upregulation of CDK1 contributes to medroxyprogesterone acetate (MPA) resistance in cancer-associated fibroblasts of the endometrium
The response to medroxyprogesterone acetate (MPA) decreases as endometrial disease progresses from the benign to malignancy. In a mouse model, progesterone receptor (PR) expression in normal fibroblasts is accountable for the MPA's inhibitory effects in cancer cells. However, it is still unclea...
Saved in:
Main Authors: | Omar, Intan Sofia, Adenan, Noor Azmi Mat, Godoy, Alejandro, Teo, Ik Hui, Gunasagran, Yogeeta, Chung, Ivy |
---|---|
Format: | Article |
Published: |
Academic Press
2022
|
Subjects: | |
Online Access: | http://eprints.um.edu.my/41116/ |
Tags: |
Add Tag
No Tags, Be the first to tag this record!
|
Similar Items
-
Effects of medroxyprogesterone acetate (MPA) in activating progesterone receptor signaling in benign and cancer-associated fibroblasts of the endometrium
by: Chung, I., et al.
Published: (2017) -
MPA alters metabolic phenotype of endometrial cancer-associated fibroblasts from obese women via IRS2 signaling
by: Omar, Intan Sofia, et al.
Published: (2022) -
Medroxyprogesterone acetate attenuates demyelination, modulating microglia activation in a cuprizone neurotoxic demyelinating mouse model
by: Mohammadi, Maryam, et al.
Published: (2021) -
A Rare Presentation of Carcinoma Endometrium
by: Myat, San Yi, et al.
Published: (2016) -
Gene expression of CDK6 and CCND1 genes in basal cell carcinoma
by: Eshkoor, Sima Ataollahi, et al.
Published: (2008)