Hepatoprotective potential of a novel quinazoline derivative in thioacetamide-induced liver toxicity

• Main Authors: Salama, Suzy, Kue, Chin Siang, Mohamad, Haryanti, Omer, Fatima, Ibrahim, Mohamed Yousif, Abdulla, Mahmood, Ali, Hapipah, Mariod, Abdalbasit, Jayash, Soher Nagi
• Format: Article
• Published: Frontiers Media 2022
• Subjects: QD Chemistry; R Medicine; RM Therapeutics. Pharmacology
• Online Access: http://eprints.um.edu.my/40887/

The compound quinazoline Q-Br, 3-(5-bromo-2-hydroxybenzylideneamino)-2-(5-bromo-2 hydroxyphenyl) 2,3-dihydroquinazoline-4(1H)-one (Q-Br) was evaluated for its antioxidant capacity and potential hepatoprotectivity against sub-chronic liver toxicity induced by thioacetamide in rats. Materials and Meth...