Dystrophin gene analysis in Duchenne/Becker dystrophy in a Malaysian population using multiplex polymerase chain reaction

• Main Authors: Tan, J., Chan, J.H.M., Tan, K.L., Annuar, A.A., Lee, M.K., Goh, K.J., Wong, Kum Thong
• Format: Article
• Language: English
• Published: 2010
• Subjects: R Medicine
• Online Access: http://eprints.um.edu.my/3709/1/Dystrophin_gene_analysis_in_DuchenneBecker_dystrophy.pdf; http://eprints.um.edu.my/3709/

Dystrophinopathy is the commonest form of muscular dystrophy and comprises clinically recognized forms, Duchenne dystrophy and Becker dystrophy. Mutations in the dystrophin gene which consist of large gene deletions (65), duplications (5) and point mutations (30) are responsible for reducing the amo...