Minor modifications to the structure of tunicamycin lead to loss of the biological-activity of the antibiotic
Three analogues of tunicamycin, each with minor alterations in structure in different regions of the molecule, have been employed to study the effects of such modifications upon the biological activity of the antibiotic. The data indicate that any modification of structure results in loss of the abi...
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Main Authors: | Hashim, Onn Haji, Cushley, W. |
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Format: | Article |
Published: |
1987
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Online Access: | http://eprints.um.edu.my/3455/ http://www.sciencedirect.com/science/article/pii/0304416587900444 |
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