Minor modifications to the structure of tunicamycin lead to loss of the biological-activity of the antibiotic

Three analogues of tunicamycin, each with minor alterations in structure in different regions of the molecule, have been employed to study the effects of such modifications upon the biological activity of the antibiotic. The data indicate that any modification of structure results in loss of the abi...

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Bibliographic Details
Main Authors: Hashim, Onn Haji, Cushley, W.
Format: Article
Published: 1987
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Online Access:http://eprints.um.edu.my/3455/
http://www.sciencedirect.com/science/article/pii/0304416587900444
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