Nutritional profile, antioxidative and antihyperglycemic properties of padina tetrastromatica from Tioman Island, Malaysia
Seaweeds are an important ingredient of functional foods recommended for daily food, due to their unique compositions and nutritional value. Padina tetrastromatica is a brown edible seaweed that is commonly found along the coastal regions of Peninsular Malaysia and consumed as food by some coastal c...
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my.um.eprints.344562022-09-14T01:06:50Z http://eprints.um.edu.my/34456/ Nutritional profile, antioxidative and antihyperglycemic properties of padina tetrastromatica from Tioman Island, Malaysia Palaniveloo, Kishneth Yee-Yinn, Liaw Jia-Qi, Leong Chelliah, Alvin Sze-Looi, Song Nagappan, Thilahgavani Razak, Shariza Abdul Dua, Kamal Chellian, Jestin Chellappan, Dinesh Kumar Kunnath, Anil Philip GC Oceanography GE Environmental Sciences Seaweeds are an important ingredient of functional foods recommended for daily food, due to their unique compositions and nutritional value. Padina tetrastromatica is a brown edible seaweed that is commonly found along the coastal regions of Peninsular Malaysia and consumed as food by some coastal communities. This study investigates the nutritional and antihyperglycaemic potential of P. tetrastromatica extracts, which is generally accepted as an important functional food. In our methodology, we induced diabetes intraperitoneally in experimental animals with a dose of 65 mg kg(-1) body weight of streptozotocin. Oral treatment with 200 and 400 mg kg(-1) of P. tetrastromatica ethanolic and ethyl acetate extracts were initiated, respectively, to experimental rats once daily for 18 days. Metformin was used as the positive control. Biochemical estimations and histopathological analysis were included in this study. Treatment with P. tetrastromatica extracts significantly lowered the plasma glucose levels in Streptozotocin-induced diabetic rats. In addition, P. tetrastromatica extract treatment also showed a significant reduction in serum alanine transaminase levels. However, no significant changes were observed in serum aspartate transaminase levels. The ethyl acetate extract of P. tetrastromatica at 400 mg kg(-1) dose shows some nephroprotective effect, which is observed from the significant increase in the plasma albumin levels. Histopathological evaluation revealed no marked morphological changes in tissues of the isolated organs of the ethyl acetate extract-treated group, revealing the safe nature of P. tetrastromatica. MDPI 2021-08 Article PeerReviewed Palaniveloo, Kishneth and Yee-Yinn, Liaw and Jia-Qi, Leong and Chelliah, Alvin and Sze-Looi, Song and Nagappan, Thilahgavani and Razak, Shariza Abdul and Dua, Kamal and Chellian, Jestin and Chellappan, Dinesh Kumar and Kunnath, Anil Philip (2021) Nutritional profile, antioxidative and antihyperglycemic properties of padina tetrastromatica from Tioman Island, Malaysia. Foods, 10 (8). ISSN 2304-8158, DOI https://doi.org/10.3390/foods10081932 <https://doi.org/10.3390/foods10081932>. 10.3390/foods10081932 |
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GC Oceanography GE Environmental Sciences Palaniveloo, Kishneth Yee-Yinn, Liaw Jia-Qi, Leong Chelliah, Alvin Sze-Looi, Song Nagappan, Thilahgavani Razak, Shariza Abdul Dua, Kamal Chellian, Jestin Chellappan, Dinesh Kumar Kunnath, Anil Philip Nutritional profile, antioxidative and antihyperglycemic properties of padina tetrastromatica from Tioman Island, Malaysia |
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Seaweeds are an important ingredient of functional foods recommended for daily food, due to their unique compositions and nutritional value. Padina tetrastromatica is a brown edible seaweed that is commonly found along the coastal regions of Peninsular Malaysia and consumed as food by some coastal communities. This study investigates the nutritional and antihyperglycaemic potential of P. tetrastromatica extracts, which is generally accepted as an important functional food. In our methodology, we induced diabetes intraperitoneally in experimental animals with a dose of 65 mg kg(-1) body weight of streptozotocin. Oral treatment with 200 and 400 mg kg(-1) of P. tetrastromatica ethanolic and ethyl acetate extracts were initiated, respectively, to experimental rats once daily for 18 days. Metformin was used as the positive control. Biochemical estimations and histopathological analysis were included in this study. Treatment with P. tetrastromatica extracts significantly lowered the plasma glucose levels in Streptozotocin-induced diabetic rats. In addition, P. tetrastromatica extract treatment also showed a significant reduction in serum alanine transaminase levels. However, no significant changes were observed in serum aspartate transaminase levels. The ethyl acetate extract of P. tetrastromatica at 400 mg kg(-1) dose shows some nephroprotective effect, which is observed from the significant increase in the plasma albumin levels. Histopathological evaluation revealed no marked morphological changes in tissues of the isolated organs of the ethyl acetate extract-treated group, revealing the safe nature of P. tetrastromatica. |
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Article |
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Palaniveloo, Kishneth Yee-Yinn, Liaw Jia-Qi, Leong Chelliah, Alvin Sze-Looi, Song Nagappan, Thilahgavani Razak, Shariza Abdul Dua, Kamal Chellian, Jestin Chellappan, Dinesh Kumar Kunnath, Anil Philip |
author_facet |
Palaniveloo, Kishneth Yee-Yinn, Liaw Jia-Qi, Leong Chelliah, Alvin Sze-Looi, Song Nagappan, Thilahgavani Razak, Shariza Abdul Dua, Kamal Chellian, Jestin Chellappan, Dinesh Kumar Kunnath, Anil Philip |
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Palaniveloo, Kishneth |
title |
Nutritional profile, antioxidative and antihyperglycemic properties of padina tetrastromatica from Tioman Island, Malaysia |
title_short |
Nutritional profile, antioxidative and antihyperglycemic properties of padina tetrastromatica from Tioman Island, Malaysia |
title_full |
Nutritional profile, antioxidative and antihyperglycemic properties of padina tetrastromatica from Tioman Island, Malaysia |
title_fullStr |
Nutritional profile, antioxidative and antihyperglycemic properties of padina tetrastromatica from Tioman Island, Malaysia |
title_full_unstemmed |
Nutritional profile, antioxidative and antihyperglycemic properties of padina tetrastromatica from Tioman Island, Malaysia |
title_sort |
nutritional profile, antioxidative and antihyperglycemic properties of padina tetrastromatica from tioman island, malaysia |
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MDPI |
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2021 |
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http://eprints.um.edu.my/34456/ |
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1744649180913074176 |
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13.18916 |