Breast cancer in a multi-ethnic Asian setting: results from the Singapore-Malaysia hospital-based breast cancer registry

Two hospital-based breast cancer databases (University Malaya Medical Center, Malaysia n = 1513 and National University Hospital, Singapore n = 2545) were merged into a regional registry of breast cancer patients diagnosed between 1990 and 2007. A review of the data found 51% of patients diagnosed b...

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Main Authors: Pathy, Nirmala Bhoo, Yip, Cheng Har, Mohd Taib, Nur Aishah, Hartman, Mikael, Saxena, Nakul, Iau, Philip, Bulgiba, Awang, Lee, Soo Chin, Lim, S.E., Wong, John E.L., Verkooijen, Helena M.
Format: Article
Language:English
Published: Elsevier 2011
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Online Access:http://eprints.um.edu.my/3058/1/Breast_cancer_in_a_multi-ethnic_Asian_setting_Results_from_the_Singapore-Malaysia.pdf
http://eprints.um.edu.my/3058/
https://doi.org/10.1016/j.breast.2011.01.015
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spelling my.um.eprints.30582019-11-15T08:31:16Z http://eprints.um.edu.my/3058/ Breast cancer in a multi-ethnic Asian setting: results from the Singapore-Malaysia hospital-based breast cancer registry Pathy, Nirmala Bhoo Yip, Cheng Har Mohd Taib, Nur Aishah Hartman, Mikael Saxena, Nakul Iau, Philip Bulgiba, Awang Lee, Soo Chin Lim, S.E. Wong, John E.L. Verkooijen, Helena M. R Medicine Two hospital-based breast cancer databases (University Malaya Medical Center, Malaysia n = 1513 and National University Hospital, Singapore n = 2545) were merged into a regional registry of breast cancer patients diagnosed between 1990 and 2007. A review of the data found 51% of patients diagnosed before the age of 50 years. and 72% percent of the women were Chinese followed by Malays (16%), Indians (8%), and other races (4%). Median tumor size at presentation was 26 mm and about 25% of patients presented with TNM stage III or IV disease. Most tumors were of ductal histology (87%). Fifty-seven percent of tumors were estrogen receptor positive and 40% were poorly differentiated. Of those patients who had surgery, 70% had mastectomy while 30% had breast conserving surgery. Overall, chemotherapy was administered to 56% of patients and hormonal treatment to 60%. Five-year overall survival was 82.5% in patients with TNM stage 0 to stage II cancer, and 30.2% in those with later stages. (C) 2011 Elsevier Ltd. All rights reserved. Elsevier 2011 Article PeerReviewed application/pdf en http://eprints.um.edu.my/3058/1/Breast_cancer_in_a_multi-ethnic_Asian_setting_Results_from_the_Singapore-Malaysia.pdf Pathy, Nirmala Bhoo and Yip, Cheng Har and Mohd Taib, Nur Aishah and Hartman, Mikael and Saxena, Nakul and Iau, Philip and Bulgiba, Awang and Lee, Soo Chin and Lim, S.E. and Wong, John E.L. and Verkooijen, Helena M. (2011) Breast cancer in a multi-ethnic Asian setting: results from the Singapore-Malaysia hospital-based breast cancer registry. The Breast, 20 (Spp.2). S75-S80. ISSN 0960-9776 https://doi.org/10.1016/j.breast.2011.01.015 doi:10.1016/j.breast.2011.01.015
institution Universiti Malaya
building UM Library
collection Institutional Repository
continent Asia
country Malaysia
content_provider Universiti Malaya
content_source UM Research Repository
url_provider http://eprints.um.edu.my/
language English
topic R Medicine
spellingShingle R Medicine
Pathy, Nirmala Bhoo
Yip, Cheng Har
Mohd Taib, Nur Aishah
Hartman, Mikael
Saxena, Nakul
Iau, Philip
Bulgiba, Awang
Lee, Soo Chin
Lim, S.E.
Wong, John E.L.
Verkooijen, Helena M.
Breast cancer in a multi-ethnic Asian setting: results from the Singapore-Malaysia hospital-based breast cancer registry
description Two hospital-based breast cancer databases (University Malaya Medical Center, Malaysia n = 1513 and National University Hospital, Singapore n = 2545) were merged into a regional registry of breast cancer patients diagnosed between 1990 and 2007. A review of the data found 51% of patients diagnosed before the age of 50 years. and 72% percent of the women were Chinese followed by Malays (16%), Indians (8%), and other races (4%). Median tumor size at presentation was 26 mm and about 25% of patients presented with TNM stage III or IV disease. Most tumors were of ductal histology (87%). Fifty-seven percent of tumors were estrogen receptor positive and 40% were poorly differentiated. Of those patients who had surgery, 70% had mastectomy while 30% had breast conserving surgery. Overall, chemotherapy was administered to 56% of patients and hormonal treatment to 60%. Five-year overall survival was 82.5% in patients with TNM stage 0 to stage II cancer, and 30.2% in those with later stages. (C) 2011 Elsevier Ltd. All rights reserved.
format Article
author Pathy, Nirmala Bhoo
Yip, Cheng Har
Mohd Taib, Nur Aishah
Hartman, Mikael
Saxena, Nakul
Iau, Philip
Bulgiba, Awang
Lee, Soo Chin
Lim, S.E.
Wong, John E.L.
Verkooijen, Helena M.
author_facet Pathy, Nirmala Bhoo
Yip, Cheng Har
Mohd Taib, Nur Aishah
Hartman, Mikael
Saxena, Nakul
Iau, Philip
Bulgiba, Awang
Lee, Soo Chin
Lim, S.E.
Wong, John E.L.
Verkooijen, Helena M.
author_sort Pathy, Nirmala Bhoo
title Breast cancer in a multi-ethnic Asian setting: results from the Singapore-Malaysia hospital-based breast cancer registry
title_short Breast cancer in a multi-ethnic Asian setting: results from the Singapore-Malaysia hospital-based breast cancer registry
title_full Breast cancer in a multi-ethnic Asian setting: results from the Singapore-Malaysia hospital-based breast cancer registry
title_fullStr Breast cancer in a multi-ethnic Asian setting: results from the Singapore-Malaysia hospital-based breast cancer registry
title_full_unstemmed Breast cancer in a multi-ethnic Asian setting: results from the Singapore-Malaysia hospital-based breast cancer registry
title_sort breast cancer in a multi-ethnic asian setting: results from the singapore-malaysia hospital-based breast cancer registry
publisher Elsevier
publishDate 2011
url http://eprints.um.edu.my/3058/1/Breast_cancer_in_a_multi-ethnic_Asian_setting_Results_from_the_Singapore-Malaysia.pdf
http://eprints.um.edu.my/3058/
https://doi.org/10.1016/j.breast.2011.01.015
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