5-Azacytidine pretreatment confers transient upregulation of proliferation and stemness in human mesenchymal stem cells

• Main Authors: Ong, Agnes Lee Chen, Lee, Sau Har, Aung, Shuh Wen, Khaing, Si Lay, Ramasamy, Thamil Selvee
• Format: Article
• Published: Elsevier 2021
• Subjects: QR Microbiology
• Online Access: http://eprints.um.edu.my/26836/; https://doi.org/10.1016/j.cdev.2021.203659

Successful outcomes of cell-based therapeutic is highly-dependent on quality and quantity of the cells. Epigenetic modifiers are known to modulate cell fates via reprogramming, hence it is plausible to use them in enhancing the plasticity of mesenchymal stem cells. In this study, we aimed to study t...