Directional capacity of human mesenchymal stem cells to support hematopoietic stem cell proliferation in vitro

• Main Authors: Boroojerdi, Mohadese Hashem, Sarmadi, Vahid Hosseinpour, Maqbool, Maryam, Ling, King Hwa, Safarzadeh Kozani, Pooria, Safarzadeh Kozani, Pouya, Ramasamy, Rajesh
• Format: Article
• Published: Elsevier B.V. 2022
• Online Access: http://psasir.upm.edu.my/id/eprint/100970/; https://www.sciencedirect.com/science/article/pii/S0378111922000373

Objectives: Hematopoietic stem cells (HSCs) reside in a specialised microenvironment in the bone marrow, which is majorly composed of mesenchymal stem cells (MSCs) and its' derivatives. This study aimed to investigate the regulatory role of MSCs to decipher the cellular and humoral communicatio...