Explanation of unusual behaviour in the acidic hydrolytic cleavage of N-(2′-methoxyphenyl)phthalimide under typical reaction conditions

• Main Authors: Sim, Yoke Leng, Khan, Mohammad Niyaz
• Format: Article
• Published: SAGE Publications 2009
• Subjects: Q Science (General); QD Chemistry
• Online Access: http://eprints.um.edu.my/25658/; https://doi.org/10.3184/146867809X471117

Pseudo-first-order rate constants, kobs, for hydrolysis of N-(2′-methoxyphenyl)- phthalimide (1) show a nonlinear decrease with the increase in [HCl] over the range 5×10-3 - 1:0M at 2:0×10-4M 1, 1.0M ionic strength (μ, by NaCl) and 35°C. White fluffy precipitates have been found to appear into the r...