Expression of p53 N-terminal isoforms in B-cell precursor acute lymphoblastic leukemia and its correlation with clinicopathological profiles

Background: TP53 mutations occur in only about 3% of primary and 10-20% of relapse B-cell precursor acute lymphoblastic leukaemia (BCP-ALL). However, alternative mechanisms may contribute to functionally impairing the p53 pathway in the absence of a mutation. Candidate mechanisms include overexpress...

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Bibliographic Details
Main Authors: Oh, Lixian, Hainaut, Pierre, Blanchet, Sandrine, Ariffin, Hany
Format: Article
Published: BioMed Central 2020
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Online Access:http://eprints.um.edu.my/25503/
https://doi.org/10.1186/s12885-020-6599-8
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