Singaporentine A: A New Indole Alkaloid from Kopsia singapurensis Ridl.

Study on chemical constituents from the leaves of Kopsia singapurensis (Apocynaceae) yielded a new indole alkaloid, singaporentine A (1) together with two known alkaloids, kopsifoline A (2) and kopsininic acid (3). The structure of 1 was elucidated by combination of various spectroscopic methods suc...

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Main Authors: Awang, Khalijah, Ahmad, Kartini, Thomas, Noel Francis, Hirasawa, Yusuke, Takeya, Koichi, Mukhtar, Mat Ropi, Mohamad, Khalit, Morita, Hiroshi
Format: Article
Published: The Japan Institute of Heterocyclic Chemistry 2008
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Online Access:http://eprints.um.edu.my/25494/
https://doi.org/10.3987/COM-08-11438
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spelling my.um.eprints.254942020-09-01T08:38:23Z http://eprints.um.edu.my/25494/ Singaporentine A: A New Indole Alkaloid from Kopsia singapurensis Ridl. Awang, Khalijah Ahmad, Kartini Thomas, Noel Francis Hirasawa, Yusuke Takeya, Koichi Mukhtar, Mat Ropi Mohamad, Khalit Morita, Hiroshi QD Chemistry RS Pharmacy and materia medica Study on chemical constituents from the leaves of Kopsia singapurensis (Apocynaceae) yielded a new indole alkaloid, singaporentine A (1) together with two known alkaloids, kopsifoline A (2) and kopsininic acid (3). The structure of 1 was elucidated by combination of various spectroscopic methods such as MS, UV, IR, ID and 2D NMR. Singaporentine A exhibited cytotoxic activity against P388 murine leukemia cells. © 2008 The Japan Institute of Heterocyclic Chemistry. The Japan Institute of Heterocyclic Chemistry 2008 Article PeerReviewed Awang, Khalijah and Ahmad, Kartini and Thomas, Noel Francis and Hirasawa, Yusuke and Takeya, Koichi and Mukhtar, Mat Ropi and Mohamad, Khalit and Morita, Hiroshi (2008) Singaporentine A: A New Indole Alkaloid from Kopsia singapurensis Ridl. Heterocycles, 75 (12). pp. 3051-3056. ISSN 0385-5414 https://doi.org/10.3987/COM-08-11438 doi:10.3987/COM-08-11438
institution Universiti Malaya
building UM Library
collection Institutional Repository
continent Asia
country Malaysia
content_provider Universiti Malaya
content_source UM Research Repository
url_provider http://eprints.um.edu.my/
topic QD Chemistry
RS Pharmacy and materia medica
spellingShingle QD Chemistry
RS Pharmacy and materia medica
Awang, Khalijah
Ahmad, Kartini
Thomas, Noel Francis
Hirasawa, Yusuke
Takeya, Koichi
Mukhtar, Mat Ropi
Mohamad, Khalit
Morita, Hiroshi
Singaporentine A: A New Indole Alkaloid from Kopsia singapurensis Ridl.
description Study on chemical constituents from the leaves of Kopsia singapurensis (Apocynaceae) yielded a new indole alkaloid, singaporentine A (1) together with two known alkaloids, kopsifoline A (2) and kopsininic acid (3). The structure of 1 was elucidated by combination of various spectroscopic methods such as MS, UV, IR, ID and 2D NMR. Singaporentine A exhibited cytotoxic activity against P388 murine leukemia cells. © 2008 The Japan Institute of Heterocyclic Chemistry.
format Article
author Awang, Khalijah
Ahmad, Kartini
Thomas, Noel Francis
Hirasawa, Yusuke
Takeya, Koichi
Mukhtar, Mat Ropi
Mohamad, Khalit
Morita, Hiroshi
author_facet Awang, Khalijah
Ahmad, Kartini
Thomas, Noel Francis
Hirasawa, Yusuke
Takeya, Koichi
Mukhtar, Mat Ropi
Mohamad, Khalit
Morita, Hiroshi
author_sort Awang, Khalijah
title Singaporentine A: A New Indole Alkaloid from Kopsia singapurensis Ridl.
title_short Singaporentine A: A New Indole Alkaloid from Kopsia singapurensis Ridl.
title_full Singaporentine A: A New Indole Alkaloid from Kopsia singapurensis Ridl.
title_fullStr Singaporentine A: A New Indole Alkaloid from Kopsia singapurensis Ridl.
title_full_unstemmed Singaporentine A: A New Indole Alkaloid from Kopsia singapurensis Ridl.
title_sort singaporentine a: a new indole alkaloid from kopsia singapurensis ridl.
publisher The Japan Institute of Heterocyclic Chemistry
publishDate 2008
url http://eprints.um.edu.my/25494/
https://doi.org/10.3987/COM-08-11438
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score 13.211869