Microwave synthesis of hydroxyapatite encumbered with ascorbic acid intended for drug leaching studies
The characteristics properties of hydroxyapatite (HAP, Ca10 (PO4)6(OH) 2) namely, bioactivity, biocompatibility, osteoconductive and adsorption capacity can be tailored over wide assortments by governing the particle composition, particle dimensions, and structure. Pure hydroxyapatite (HAP) nanopart...
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my.um.eprints.254362020-08-25T03:17:06Z http://eprints.um.edu.my/25436/ Microwave synthesis of hydroxyapatite encumbered with ascorbic acid intended for drug leaching studies Padmanabhan, Varun Prasath Kulandaivelu, Ravichandran Santhana Panneer, Devendrapandi Vivekananthan, S. Sagadevan, Suresh Lett, J. Anita Q Science (General) QC Physics QD Chemistry The characteristics properties of hydroxyapatite (HAP, Ca10 (PO4)6(OH) 2) namely, bioactivity, biocompatibility, osteoconductive and adsorption capacity can be tailored over wide assortments by governing the particle composition, particle dimensions, and structure. Pure hydroxyapatite (HAP) nanoparticles were synthesized by a simple straightforward approach using microwave irradiation method. The prepared HAP samples were studied for phase purity using X-ray diffractometer (XRD); functional group analysis using Fourier transform Infrared (FTIR) spectroscopy. Scanning electron microscopy (SEM) and Transmission electron microscopy (TEM) was used to examine the assembling of the HAP particles. These outcomes validate that shorter rod–like HAP particles can be organized by microwave irradiation technique. The synthesized HAP samples were loaded with ascorbic acid to analyze it’s in vitro drug release studies and its biocompatibility was confirmed by means of MTT assay using Saos-2 cell lines (Human Osteosarcoma Cell Line). © 2019, © 2019 Informa UK Limited, trading as Taylor & Francis Group. Taylor & Francis 2020 Article PeerReviewed Padmanabhan, Varun Prasath and Kulandaivelu, Ravichandran and Santhana Panneer, Devendrapandi and Vivekananthan, S. and Sagadevan, Suresh and Lett, J. Anita (2020) Microwave synthesis of hydroxyapatite encumbered with ascorbic acid intended for drug leaching studies. Materials Research Innovations, 24 (3). pp. 171-178. ISSN 1432-8917 https://doi.org/10.1080/14328917.2019.1624940 doi:10.1080/14328917.2019.1624940 |
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Q Science (General) QC Physics QD Chemistry Padmanabhan, Varun Prasath Kulandaivelu, Ravichandran Santhana Panneer, Devendrapandi Vivekananthan, S. Sagadevan, Suresh Lett, J. Anita Microwave synthesis of hydroxyapatite encumbered with ascorbic acid intended for drug leaching studies |
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The characteristics properties of hydroxyapatite (HAP, Ca10 (PO4)6(OH) 2) namely, bioactivity, biocompatibility, osteoconductive and adsorption capacity can be tailored over wide assortments by governing the particle composition, particle dimensions, and structure. Pure hydroxyapatite (HAP) nanoparticles were synthesized by a simple straightforward approach using microwave irradiation method. The prepared HAP samples were studied for phase purity using X-ray diffractometer (XRD); functional group analysis using Fourier transform Infrared (FTIR) spectroscopy. Scanning electron microscopy (SEM) and Transmission electron microscopy (TEM) was used to examine the assembling of the HAP particles. These outcomes validate that shorter rod–like HAP particles can be organized by microwave irradiation technique. The synthesized HAP samples were loaded with ascorbic acid to analyze it’s in vitro drug release studies and its biocompatibility was confirmed by means of MTT assay using Saos-2 cell lines (Human Osteosarcoma Cell Line). © 2019, © 2019 Informa UK Limited, trading as Taylor & Francis Group. |
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Padmanabhan, Varun Prasath Kulandaivelu, Ravichandran Santhana Panneer, Devendrapandi Vivekananthan, S. Sagadevan, Suresh Lett, J. Anita |
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Padmanabhan, Varun Prasath Kulandaivelu, Ravichandran Santhana Panneer, Devendrapandi Vivekananthan, S. Sagadevan, Suresh Lett, J. Anita |
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Padmanabhan, Varun Prasath |
title |
Microwave synthesis of hydroxyapatite encumbered with ascorbic acid intended for drug leaching studies |
title_short |
Microwave synthesis of hydroxyapatite encumbered with ascorbic acid intended for drug leaching studies |
title_full |
Microwave synthesis of hydroxyapatite encumbered with ascorbic acid intended for drug leaching studies |
title_fullStr |
Microwave synthesis of hydroxyapatite encumbered with ascorbic acid intended for drug leaching studies |
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Microwave synthesis of hydroxyapatite encumbered with ascorbic acid intended for drug leaching studies |
title_sort |
microwave synthesis of hydroxyapatite encumbered with ascorbic acid intended for drug leaching studies |
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Taylor & Francis |
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2020 |
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http://eprints.um.edu.my/25436/ https://doi.org/10.1080/14328917.2019.1624940 |
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