Proliferating cell nuclear antigen (PCNA) and p53 in epithelial dysplasia and squamous cell carcinoma of oral mucosa - a marker for poor tumor differentiation, increasing nuclear atypia and invasiveness

• Main Authors: Lan, H.A., Zain, R.B., Saitoh, M., Muramatsu, Y., Shrestha, P., Mori, M.
• Format: Article
• Language: English
• Published: INT INST ANTICANCER RESEARCH 1996
• Subjects: Oral surger
• Online Access: http://eprints.um.edu.my/2536/1/Proliferating_cell_nuclear_antigen_%28PCNA%29_and_p53_in_epithelial_dysplasia_s.pdf; http://eprints.um.edu.my/2536/

The immunohistochemical expression of proliferating cell nuclear antigen (PCNA) and p53 was investigated in 9 cases of epithelial dysplasia and 38 cases of squamous cell carcinoma of the oral cavity. The intensity of immunoreactivity for each marker was assessed using a semiquantitative grading syst...